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Effectiveness of 4-1BB-costimulated HER2-targeted chimeric antigen receptor T cell therapy for synovial sarcoma

BACKGROUND: Synovial sarcoma is a rare malignant soft-tissue tumor that is prevalent in adolescents and young adults, and poor prognosis has been reported in patients with metastatic lesions. Chimeric antigen receptor (CAR) T-cell therapy is an emerging novel therapy for solid tumors; however, its a...

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Detalles Bibliográficos
Autores principales: Murayama, Yudai, Kawashima, Hiroyuki, Kubo, Nobuhiro, Shin, Chansu, Kasahara, Yasushi, Imamura, Masaru, Oike, Naoki, Ariizumi, Takashi, Saitoh, Akihiko, Mihara, Keichiro, Umezu, Hajime, Ogose, Akira, Imai, Chihaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461377/
https://www.ncbi.nlm.nih.gov/pubmed/34555727
http://dx.doi.org/10.1016/j.tranon.2021.101227