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Insights into evolution and coexistence of the colibactin- and yersiniabactin secondary metabolite determinants in enterobacterial populations

The bacterial genotoxin colibactin interferes with the eukaryotic cell cycle by causing dsDNA breaks. It has been linked to bacterially induced colorectal cancer in humans. Colibactin is encoded by a 54 kb genomic region in Enterobacteriaceae. The colibactin genes commonly co-occur with the yersinia...

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Detalles Bibliográficos
Autores principales: Wami, Haleluya, Wallenstein, Alexander, Sauer, Daniel, Stoll, Monika, von Bünau, Rudolf, Oswald, Eric, Müller, Rolf, Dobrindt, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461471/
https://www.ncbi.nlm.nih.gov/pubmed/34128785
http://dx.doi.org/10.1099/mgen.0.000577