Sinomenine hydrochloride ameliorates dextran sulfate sodium-induced colitis in mice by modulating the gut microbiota composition whilst suppressing the activation of the NLRP3 inflammasome

Sinomenine is a pure alkaloid that can be isolated from the root of Sinomenium acutum and has been found to exert anti-inflammatory and immunosuppressive effects. The present study investigated the effects of sinomenine hydrochloride (SIN) on inflammation and the gut microbiota composition in the co...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Chen, Shuai, Gu, Wenxian, Sun, Xiao, Wang, Linxiao, Tang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461516/
https://www.ncbi.nlm.nih.gov/pubmed/34630642
http://dx.doi.org/10.3892/etm.2021.10722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461516/
https://www.ncbi.nlm.nih.gov/pubmed/34630642
http://dx.doi.org/10.3892/etm.2021.10722

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