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Exosomes derived from PC-3 cells suppress osteoclast differentiation by downregulating miR-148a and blocking the PI3K/AKT/mTOR pathway

Prostate cancer is a leading malignancy in men that can also disrupt the bone tissue balance. Among all urological cancers, prostate cancer is associated with the highest rate of bone metastases, which can greatly reduce a patient's quality of life. In recent years, cell-derived exosomes, which...

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Detalles Bibliográficos
Autores principales: Tian, Gaoqiang, Hu, Konghe, Qiu, Sujun, Xie, Yingming, Cao, Yanlin, Ni, Songjia, Zhang, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461599/
https://www.ncbi.nlm.nih.gov/pubmed/34630659
http://dx.doi.org/10.3892/etm.2021.10739