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Ononin alleviates H(2)O(2)-induced cardiomyocyte apoptosis and improves cardiac function by activating the AMPK/mTOR/autophagy pathway

Ononin (ON) is an isoflavone with numerous reported bioactivities, including anti-oxidative, anti-inflammatory and neuroprotective effects. Autophagy is a critical homeostatic process in the body that has been reported to closely associate with the apoptotic processes of cardiomyocytes. Using flow c...

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Detalles Bibliográficos
Autores principales: Pan, Rongrong, Zhuang, Qin, Wang, Jiangtin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461629/
https://www.ncbi.nlm.nih.gov/pubmed/34584565
http://dx.doi.org/10.3892/etm.2021.10742