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Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease

BACKGROUND: Although pathological studies usually indicate pure dopaminergic neuronal degeneration in patients with parkin (PRKN) mutations, there is no evidence to date regarding white matter (WM) pathology. A previous diffusion MRI study has revealed WM microstructural alterations caused by system...

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Detalles Bibliográficos
Autores principales: Koinuma, Takahiro, Hatano, Taku, Kamagata, Koji, Andica, Christina, Mori, Akio, Ogawa, Takashi, Takeshige-Amano, Haruka, Uchida, Wataru, Saiki, Shinji, Okuzumi, Ayami, Ueno, Shin-Ichi, Oji, Yutaka, Saito, Yuya, Hori, Masaaki, Aoki, Shigeki, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461664/
https://www.ncbi.nlm.nih.gov/pubmed/33896850
http://dx.doi.org/10.3233/JPD-202495