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Neuronal Cell Cycle Re-Entry Enhances Neuropathological Features in App(NLF) Knock-In Mice
BACKGROUND: Aberrant cell cycle re-entry is a well-documented process occurring early in Alzheimer’s disease (AD). This is an early feature of the disease and may contribute to disease pathogenesis. OBJECTIVE: To assess the effect of forced neuronal cell cycle re-entry in mice expressing humanized A...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461670/ https://www.ncbi.nlm.nih.gov/pubmed/34219712 http://dx.doi.org/10.3233/JAD-210091 |