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Neuronal Cell Cycle Re-Entry Enhances Neuropathological Features in App(NLF) Knock-In Mice

BACKGROUND: Aberrant cell cycle re-entry is a well-documented process occurring early in Alzheimer’s disease (AD). This is an early feature of the disease and may contribute to disease pathogenesis. OBJECTIVE: To assess the effect of forced neuronal cell cycle re-entry in mice expressing humanized A...

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Detalles Bibliográficos
Autores principales:	Barrett, Tomás, Stangis, Katherine A., Saito, Takashi, Saido, Takaomi, Park, Kevin H.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461670/ https://www.ncbi.nlm.nih.gov/pubmed/34219712 http://dx.doi.org/10.3233/JAD-210091

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