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Aggregate Trends of Apolipoprotein E on Cognition in Transgenic Alzheimer’s Disease Mice

BACKGROUND: Apolipoprotein E (APOE) genotypes typically increase risk of amyloid-β deposition and onset of clinical Alzheimer’s disease (AD). However, cognitive assessments in APOE transgenic AD mice have resulted in discord. OBJECTIVE: Analysis of 31 peer-reviewed AD APOE mouse publications (n = 3,...

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Detalles Bibliográficos
Autores principales: Watson, Yassin, Nelson, Brenae, Kluesner, Jamie Hernandez, Tanzy, Caroline, Ramesh, Shreya, Patel, Zoey, Kluesner, Kaci Hernandez, Singh, Anita, Murthy, Vibha, Mitchell, Cassie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461675/
https://www.ncbi.nlm.nih.gov/pubmed/34334405
http://dx.doi.org/10.3233/JAD-210492