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The Locus Coeruleus in Aging and Alzheimer’s Disease: A Postmortem and Brain Imaging Review

The locus coeruleus (LC), a tiny nucleus in the brainstem and the principal site of noradrenaline synthesis, has a major role in regulating autonomic function, arousal, attention, and neuroinflammation. LC dysfunction has been linked to a range of disorders; however particular interest is given to t...

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Detalles Bibliográficos
Autores principales: Beardmore, Rebecca, Hou, Ruihua, Darekar, Angela, Holmes, Clive, Boche, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461706/
https://www.ncbi.nlm.nih.gov/pubmed/34219717
http://dx.doi.org/10.3233/JAD-210191