Segmented Linear Mixed Model Analysis Reveals Association of the APOE ɛ4 Allele with Faster Rate of Alzheimer’s Disease Dementia Progression

BACKGROUND: APOEɛ4 allele carriers present with an increased risk for late-onset Alzheimer’s disease (AD), show cognitive symptoms at an earlier age, and are more likely to transition from mild cognitive impairment (MCI) to dementia but despite this, it remains unclear whether or not the ɛ4 allele c...

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Detalles Bibliográficos
Autores principales: Chen, X. Richard, Shao, Yongzhao, Sadowski, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461709/
https://www.ncbi.nlm.nih.gov/pubmed/34120907
http://dx.doi.org/10.3233/JAD-210434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461709/
https://www.ncbi.nlm.nih.gov/pubmed/34120907
http://dx.doi.org/10.3233/JAD-210434

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