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Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats

BACKGROUND: Parkinson’s disease (PD) is a progressive neurological disorder where loss of dopamine neurons in the substantia nigra and dopamine depletion in the striatum cause characteristic motor symptoms. Currently, no treatment is able to halt the progression of PD. Glial cell line-derived neurot...

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Detalles Bibliográficos
Autores principales: Renko, Juho-Matti, Mahato, Arun Kumar, Visnapuu, Tanel, Valkonen, Konsta, Karelson, Mati, Voutilainen, Merja H., Saarma, Mart, Tuominen, Raimo K., Sidorova, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461720/
https://www.ncbi.nlm.nih.gov/pubmed/34024778
http://dx.doi.org/10.3233/JPD-202400