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Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats
BACKGROUND: Parkinson’s disease (PD) is a progressive neurological disorder where loss of dopamine neurons in the substantia nigra and dopamine depletion in the striatum cause characteristic motor symptoms. Currently, no treatment is able to halt the progression of PD. Glial cell line-derived neurot...
Autores principales: | Renko, Juho-Matti, Mahato, Arun Kumar, Visnapuu, Tanel, Valkonen, Konsta, Karelson, Mati, Voutilainen, Merja H., Saarma, Mart, Tuominen, Raimo K., Sidorova, Yulia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461720/ https://www.ncbi.nlm.nih.gov/pubmed/34024778 http://dx.doi.org/10.3233/JPD-202400 |
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