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Identification and Characterisation of cis-Regulatory Elements Upstream of the Human Receptor Tyrosine Kinase Gene MERTK

BACKGROUND: MERTK encodes a receptor tyrosine kinase that regulates immune homeostasis via phagocytosis of apoptotic cells and cytokine-mediated immunosuppression. MERTK is highly expressed in the central nervous system (CNS), specifically in myeloid derived innate immune cells and its dysregulation...

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Detalles Bibliográficos
Autores principales: Walsh, Alexander D., Johnson, Laura J., Harvey, Alexandra J., Kilpatrick, Trevor J., Binder, Michele D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461731/
https://www.ncbi.nlm.nih.gov/pubmed/34631417
http://dx.doi.org/10.3233/BPL-200102