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Identification and Characterisation of cis-Regulatory Elements Upstream of the Human Receptor Tyrosine Kinase Gene MERTK
BACKGROUND: MERTK encodes a receptor tyrosine kinase that regulates immune homeostasis via phagocytosis of apoptotic cells and cytokine-mediated immunosuppression. MERTK is highly expressed in the central nervous system (CNS), specifically in myeloid derived innate immune cells and its dysregulation...
Autores principales: | Walsh, Alexander D., Johnson, Laura J., Harvey, Alexandra J., Kilpatrick, Trevor J., Binder, Michele D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461731/ https://www.ncbi.nlm.nih.gov/pubmed/34631417 http://dx.doi.org/10.3233/BPL-200102 |
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