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Upregulation of IL-1 Receptor Antagonist by Aspirin in Glial Cells via Peroxisome Proliferator-Activated Receptor-Alpha

BACKGROUND: Neuroinflammation is a recognized aspect of Alzheimer’s disease (AD) and other neurological illnesses. Interleukin 1 receptor antagonist (IL-1Ra) is an anti-inflammatory molecule, which inhibits inflammatory molecules in different cells including brain cells. However, mechanisms for upre...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Sudipta, Prorok, Tim, Roy, Avik, Patel, Dhruv, Dasarathi, Sridevi, Pahan, Kalipada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461733/
https://www.ncbi.nlm.nih.gov/pubmed/34632302
http://dx.doi.org/10.3233/ADR-210026