Sialic Acid Ligands of CD28 Suppress Costimulation of T Cells

[Image: see text] Effector T cells comprise the cellular arm of the adaptive immune system and are essential for mounting immune responses against pathogens and cancer. To reach effector status, costimulation through CD28 is required. Here, we report that sialic acid-containing glycans on the surfac...

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Detalles Bibliográficos
Autores principales: Edgar, Landon J., Thompson, Andrew J., Vartabedian, Vincent F., Kikuchi, Chika, Woehl, Jordan L., Teijaro, John R., Paulson, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461770/
https://www.ncbi.nlm.nih.gov/pubmed/34584952
http://dx.doi.org/10.1021/acscentsci.1c00525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461770/
https://www.ncbi.nlm.nih.gov/pubmed/34584952
http://dx.doi.org/10.1021/acscentsci.1c00525

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