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Paramyxovirus replication induces the hexosamine biosynthetic pathway and mesenchymal transition via the IRE1α-XBP1s arm of the unfolded protein response

The paramyxoviridae, respiratory syncytial virus (RSV), and murine respirovirus are enveloped, negative-sense RNA viruses that are the etiological agents of vertebrate lower respiratory tract infections (LRTIs). We observed that RSV infection in human small airway epithelial cells induced accumulati...

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Detalles Bibliográficos
Autores principales: Qiao, Dianhua, Skibba, Melissa, Xu, Xiaofang, Garofalo, Roberto P., Zhao, Yingxin, Brasier, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461800/
https://www.ncbi.nlm.nih.gov/pubmed/34318710
http://dx.doi.org/10.1152/ajplung.00127.2021