Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer

INTRODUCTION: The transcription factor MYC is overexpressed in 30% of small cell lung cancer (SCLC) tumors and is known to modulate the balance between two major pathways of metabolism: glycolysis and mitochondrial respiration. This duality of MYC underscores the importance of further investigation...

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Detalles Bibliográficos
Autores principales: Cargill, Kasey R., Stewart, C. Allison, Park, Elizabeth M., Ramkumar, Kavya, Gay, Carl M., Cardnell, Robert J., Wang, Qi, Diao, Lixia, Shen, Li, Fan, You-Hong, Chan, Wai Kin, Lorenzi, Philip L., Oliver, Trudy G., Wang, Jing, Byers, Lauren A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461854/
https://www.ncbi.nlm.nih.gov/pubmed/34556188
http://dx.doi.org/10.1186/s40170-021-00270-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461854/
https://www.ncbi.nlm.nih.gov/pubmed/34556188
http://dx.doi.org/10.1186/s40170-021-00270-9

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