USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4

BACKGROUND: Glioblastomas (GBMs) are grade IV central nervous system tumors characterized by a poor prognosis and a short median overall survival. Effective induction of GBM cell death is difficult because the GBM cell population is genetically unstable, resistant to chemotherapy and highly angiogen...

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Detalles Bibliográficos
Autores principales: Pan, Tingzheng, Li, Xuetao, Li, Yanyan, Tao, Zhennan, Yao, Hui, Wu, Yue, Chen, Guangliang, Zhang, Kai, Zhou, Youxin, Huang, Yulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461901/
https://www.ncbi.nlm.nih.gov/pubmed/34556124
http://dx.doi.org/10.1186/s12935-021-02208-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461901/
https://www.ncbi.nlm.nih.gov/pubmed/34556124
http://dx.doi.org/10.1186/s12935-021-02208-z

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