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USP7 inhibition induces apoptosis in glioblastoma by enhancing ubiquitination of ARF4
BACKGROUND: Glioblastomas (GBMs) are grade IV central nervous system tumors characterized by a poor prognosis and a short median overall survival. Effective induction of GBM cell death is difficult because the GBM cell population is genetically unstable, resistant to chemotherapy and highly angiogen...
Autores principales: | Pan, Tingzheng, Li, Xuetao, Li, Yanyan, Tao, Zhennan, Yao, Hui, Wu, Yue, Chen, Guangliang, Zhang, Kai, Zhou, Youxin, Huang, Yulun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461901/ https://www.ncbi.nlm.nih.gov/pubmed/34556124 http://dx.doi.org/10.1186/s12935-021-02208-z |
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