Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint

BACKGROUND: In patients with axial spondyloarthritis (axSpA), monocytes show a pre-activated phenotype. Gut inflammation is a trigger of monocyte activation and may also affect their development in the bone marrow (BM). As gut inflammation is commonly observed in axSpA patients, we performed a detai...

Descripción completa

Detalles Bibliográficos
Autores principales: Karow, Fabian, Smiljanovic, Biljana, Grün, Joachim R., Poddubnyy, Denis, Proft, Fabian, Talpin, Alice, Hue, Christophe, Boland, Anne, Deleuze, Jean-François, Garchon, Henri-Jean, Ergenç, Ilkay, De Craemer, Ann-Sophie, Erben, Ulrike, Häupl, Thomas, Elewaut, Dirk, Breban, Maxime, Grützkau, Andreas, Syrbe, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461951/
https://www.ncbi.nlm.nih.gov/pubmed/34560894
http://dx.doi.org/10.1186/s13075-021-02623-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461951/
https://www.ncbi.nlm.nih.gov/pubmed/34560894
http://dx.doi.org/10.1186/s13075-021-02623-7

Ejemplares similares