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Enhanced osteogenic differentiation of alendronate-conjugated nanodiamonds for potential osteoporosis treatment

BACKGROUND: Alendronate (Alen) is promising material used for bone-targeted drug delivery due to its high bone affinity and therapeutic effects on bone diseases. In addition, Alen can enhance the osteogenic differentiation of osteoblastic cell. Recently, nanodiamonds (NDs) with hardness, non-toxicit...

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Detalles Bibliográficos
Autores principales: Ahn, Guk Young, Kim, Sung-Eun, Yun, Tae Hoon, Choi, Inseong, Park, Daewon, Choi, Sung-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461989/
https://www.ncbi.nlm.nih.gov/pubmed/34556181
http://dx.doi.org/10.1186/s40824-021-00231-9