Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling

Pericytes regulate vascular development, stability, and quiescence; their dysfunction contributes to diabetic retinopathy. To explore the role of insulin receptors in pericyte biology, we created pericyte insulin receptor knockout mice (PIRKO) by crossing PDGFRβ-Cre mice with insulin receptor (Insr)...

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Detalles Bibliográficos
Autores principales: Warmke, Nele, Platt, Fiona, Bruns, Alexander F, Ozber, Claire H, Haywood, Natalie J, Abudushalamu, Yilizila, Slater, Charles, Palin, Victoria, Sukumar, Piruthivi, Wheatcroft, Stephen B, Yuldasheva, Nadira Y, Kearney, Mark T, Griffin, Kathryn J, Cubbon, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462386/
https://www.ncbi.nlm.nih.gov/pubmed/34460911
http://dx.doi.org/10.1210/endocr/bqab182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462386/
https://www.ncbi.nlm.nih.gov/pubmed/34460911
http://dx.doi.org/10.1210/endocr/bqab182

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