Associations between efavirenz concentrations, pharmacogenetics and neurocognitive performance in people living with HIV in Nigeria

OBJECTIVE: Efavirenz (EFV) use is associated with neuropsychiatric side effects, which may include poor neurocognitive performance. We evaluated single nucleotide polymorphisms in genes that contribute to EFV pharmacokinetics and examined them in association with EFV concentrations in plasma and hai...

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Detalles Bibliográficos
Autores principales: Nwogu, Jacinta N., Gandhi, Monica, Owen, Andrew, Khoo, Saye H., Taiwo, Babafemi, Olagunju, Adeniyi, Berzins, Baiba, Okochi, Hideaki, Tallerico, Regina, Robertson, Kevin, Babalola, Chinedum P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462442/
https://www.ncbi.nlm.nih.gov/pubmed/34115651
http://dx.doi.org/10.1097/QAD.0000000000002984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462442/
https://www.ncbi.nlm.nih.gov/pubmed/34115651
http://dx.doi.org/10.1097/QAD.0000000000002984

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