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Associations between efavirenz concentrations, pharmacogenetics and neurocognitive performance in people living with HIV in Nigeria
OBJECTIVE: Efavirenz (EFV) use is associated with neuropsychiatric side effects, which may include poor neurocognitive performance. We evaluated single nucleotide polymorphisms in genes that contribute to EFV pharmacokinetics and examined them in association with EFV concentrations in plasma and hai...
Autores principales: | Nwogu, Jacinta N., Gandhi, Monica, Owen, Andrew, Khoo, Saye H., Taiwo, Babafemi, Olagunju, Adeniyi, Berzins, Baiba, Okochi, Hideaki, Tallerico, Regina, Robertson, Kevin, Babalola, Chinedum P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462442/ https://www.ncbi.nlm.nih.gov/pubmed/34115651 http://dx.doi.org/10.1097/QAD.0000000000002984 |
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