Social Deficits and Repetitive Behaviors Are Improved by Early Postnatal Low-Dose VPA Intervention in a Novel shank3-Deficient Zebrafish Model

Mutations of the SHANK3 gene are found in some autism spectrum disorder (ASD) patients, and animal models harboring SHANK3 mutations exhibit a variety of ASD-like behaviors, presenting a unique opportunity to explore the underlying neuropathological mechanisms and potential pharmacological treatment...

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Detalles Bibliográficos
Autores principales: Liu, Chunxue, Wang, Yi, Deng, Jingxin, Lin, Jia, Hu, Chunchun, Li, Qiang, Xu, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462462/
https://www.ncbi.nlm.nih.gov/pubmed/34566559
http://dx.doi.org/10.3389/fnins.2021.682054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462462/
https://www.ncbi.nlm.nih.gov/pubmed/34566559
http://dx.doi.org/10.3389/fnins.2021.682054

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