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Traumatic Brain Injury Impairs Systemic Vascular Function through Disruption of Inward-Rectifier Potassium Channels

Trauma can lead to widespread vascular dysfunction, but the underlying mechanisms remain largely unknown. Inward-rectifier potassium channels (Kir2.1) play a critical role in the dynamic regulation of regional perfusion and blood flow. Kir2.1 channel activity requires phosphatidylinositol 4,5-bispho...

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Detalles Bibliográficos
Autores principales: Sackheim, Adrian M, Villalba, Nuria, Sancho, Maria, Harraz, Osama F, Bonev, Adrian D, D’Alessandro, Angelo, Nemkov, Travis, Nelson, Mark T, Freeman, Kalev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462507/
https://www.ncbi.nlm.nih.gov/pubmed/34568829
http://dx.doi.org/10.1093/function/zqab018