Hydroxychloroquine Induces Apoptosis in Cholangiocarcinoma via Reactive Oxygen Species Accumulation Induced by Autophagy Inhibition

Purpose: Despite considerable efforts to improve treatment modalities for cholangiocarcinoma, a common form of malignant tumor, its long-term survival rate remains poor. Hydroxychloroquine (HCQ) is a 4-aminoquinoline derivative antimalarial drug that has antimalarial and autophagy inhibition effects...

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Detalles Bibliográficos
Autores principales: Chen, Jiaqi, Pan, Qiaoya, Bai, Yang, Chen, Xuepeng, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462510/
https://www.ncbi.nlm.nih.gov/pubmed/34568426
http://dx.doi.org/10.3389/fmolb.2021.720370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462510/
https://www.ncbi.nlm.nih.gov/pubmed/34568426
http://dx.doi.org/10.3389/fmolb.2021.720370

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