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Clinical Implications of Genomic Loss of Heterozygosity in Endometrial Carcinoma

PURPOSE: Homologous recombination deficiency, identified by homologous recombination deficiency gene alterations or high percentage of genome-wide loss of heterozygosity (gLOH), is associated with improved prognosis, platinum sensitivity (PS), and poly (ADP-ribose) polymerase inhibitor response in h...

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Detalles Bibliográficos
Autores principales: Bustamante, Bethany, Sinha, Risha, Rice, Briana, Nizam, Aaron, Shan, Weiwei, Goldberg, Gary L., John, Veena, Lin, Doug I., Danziger, Natalie, Pavlick, Dean C., Elvin, Julia A., Frimer, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462566/
https://www.ncbi.nlm.nih.gov/pubmed/34585039
http://dx.doi.org/10.1200/PO.20.00393