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Mathematical model of a personalized neoantigen cancer vaccine and the human immune system

Cancer vaccines are an important component of the cancer immunotherapy toolkit enhancing immune response to malignant cells by activating CD4(+) and CD8(+) T cells. Multiple successful clinical applications of cancer vaccines have shown good safety and efficacy. Despite the notable progress, signifi...

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Detalles Bibliográficos
Autores principales: Rodriguez Messan, Marisabel, Yogurtcu, Osman N., McGill, Joseph R., Nukala, Ujwani, Sauna, Zuben E., Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462726/
https://www.ncbi.nlm.nih.gov/pubmed/34559809
http://dx.doi.org/10.1371/journal.pcbi.1009318