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Mathematical model of a personalized neoantigen cancer vaccine and the human immune system
Cancer vaccines are an important component of the cancer immunotherapy toolkit enhancing immune response to malignant cells by activating CD4(+) and CD8(+) T cells. Multiple successful clinical applications of cancer vaccines have shown good safety and efficacy. Despite the notable progress, signifi...
Autores principales: | Rodriguez Messan, Marisabel, Yogurtcu, Osman N., McGill, Joseph R., Nukala, Ujwani, Sauna, Zuben E., Yang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462726/ https://www.ncbi.nlm.nih.gov/pubmed/34559809 http://dx.doi.org/10.1371/journal.pcbi.1009318 |
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