Quinazolin-4(3H)-one based potential multiple tyrosine kinase inhibitors with excellent cytotoxicity

A series of quinazolin-4(3H)-one derivatives were synthesised and evaluated for their cytotoxicity against human Caucasian breast adenocarcinoma (MCF-7) and human ovarian carcinoma (A2780) cell lines. Cytotoxicity of the most tested compounds was 2- to 30-fold more than the positive control lapatini...

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Detalles Bibliográficos
Autores principales: Mirgany, Tebyan O., Abdalla, Ashraf N., Arifuzzaman, Md, Motiur Rahman, A. F. M., Al-Salem, Huda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462848/
https://www.ncbi.nlm.nih.gov/pubmed/34551654
http://dx.doi.org/10.1080/14756366.2021.1972992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462848/
https://www.ncbi.nlm.nih.gov/pubmed/34551654
http://dx.doi.org/10.1080/14756366.2021.1972992

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