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Yang-Yin-Jie-Du decoction overcomes gefitinib resistance in non-small cell lung cancer via down-regulation of the PI3K/Akt signalling pathway

CONTEXT: Yang-Yin-Jie-Du Decoction (YYJDD) was used to improve gefitinib efficacy in our clinical practice, but its mechanism remains unclear. OBJECTIVE: This study explored if YYJDD could reverse gefitinib resistance. MATERIALS AND METHODS: H1975 cells were exposed to control, 10 μM gefitinib, 3.2 ...

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Detalles Bibliográficos
Autores principales: Chen, Shu-yi, Zhang, Gao-chen-xi, Shu, Qi-jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462892/
https://www.ncbi.nlm.nih.gov/pubmed/34543169
http://dx.doi.org/10.1080/13880209.2021.1972122