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The cohesin stabilizer Sororin drives G(2)-M transition and spindle assembly in mammalian oocytes

During the S phase of mitosis, Sororin is recruited by acetylated Smc3 and stabilizes sister chromatid cohesion by counteracting the Wapl-Pds5 interaction. Thereafter, Sororin is phosphorylated during prophase and translocated to the cytoplasm, where its function remains poorly understood. Here, we...

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Detalles Bibliográficos
Autores principales: Zhou, Changyin, Zhang, Xue, Miao, Yilong, Zhang, Yu, Li, Yu, Xiong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462903/
https://www.ncbi.nlm.nih.gov/pubmed/34559563
http://dx.doi.org/10.1126/sciadv.abg9335