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The cohesin stabilizer Sororin drives G(2)-M transition and spindle assembly in mammalian oocytes
During the S phase of mitosis, Sororin is recruited by acetylated Smc3 and stabilizes sister chromatid cohesion by counteracting the Wapl-Pds5 interaction. Thereafter, Sororin is phosphorylated during prophase and translocated to the cytoplasm, where its function remains poorly understood. Here, we...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462903/ https://www.ncbi.nlm.nih.gov/pubmed/34559563 http://dx.doi.org/10.1126/sciadv.abg9335 |