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Yap-Hippo Signaling Activates Mitochondrial Protection and Sustains Breast Cancer Viability under Hypoxic Stress

Yes-associated protein (Yap) is a transcriptional regulator that upregulates oncogenes and downregulates tumor repressor genes. In this study, we analyzed protein expression, RNA transcription, and signaling pathways to determine the function and mechanism of Yap in breast cancer survival during hyp...

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Detalles Bibliográficos
Autores principales: Shi, Chen, Zhang, Siyuan, Guo, Changkuo, Tie, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463197/
https://www.ncbi.nlm.nih.gov/pubmed/34567116
http://dx.doi.org/10.1155/2021/5212721