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Simultaneous and Rapid Determination of Six Tyrosine Kinase Inhibitors in Patients with Non-Small Cell Lung Cancer Using HPLC-MS/MS

OBJECTIVE: To develop a new method for quantitatively analyzing six tyrosine kinase inhibitors (gefitinib, erlotinib, icotinib, afatinib, osimertinib, and crizotinib) used in the treatment of non-small cell lung cancer (NSCLC) by liquid chromatography-tandem mass spectrometry (LC-MS/MS). METHODS: Th...

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Detalles Bibliográficos
Autores principales: Liu, Yanping, Liu, Hua, Xia, Zhewei, Wang, Zhipeng, Yun, Yunlei, Zhang, Guanying, Huang, Lifeng, Gao, Shouhong, Chen, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463214/
https://www.ncbi.nlm.nih.gov/pubmed/34567122
http://dx.doi.org/10.1155/2021/5524361