Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch/NF-κB and RAS/RAF/MEK/ERK signaling pathway

Resistance to breast cancer (BCa) chemotherapy severely hampers the patient's prognosis. MicroRNAs provide a potential therapeutic prospect for BCa. In this study, the reversal function of microRNA34a (miR34a) on doxorubicin (Dox) resistance of BCa and the possible mechanism was investigated. W...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxia, Shang, Pengfei, Yu, Bingfang, Jin, Qiuyang, Liao, Jing, Wang, Lei, Ji, Jianbo, Guo, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463267/
https://www.ncbi.nlm.nih.gov/pubmed/34589399
http://dx.doi.org/10.1016/j.apsb.2021.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463267/
https://www.ncbi.nlm.nih.gov/pubmed/34589399
http://dx.doi.org/10.1016/j.apsb.2021.06.003

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