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Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation

Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 inflammasome has been considered to be a potential therapy, the underlying mechanism through which pathway the intestinal inflammat...

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Detalles Bibliográficos
Autores principales: Lv, Qi, Xing, Yao, Liu, Jian, Dong, Dong, Liu, Yue, Qiao, Hongzhi, Zhang, Yinan, Hu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463273/
https://www.ncbi.nlm.nih.gov/pubmed/34589402
http://dx.doi.org/10.1016/j.apsb.2021.03.011