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Lonicerin targets EZH2 to alleviate ulcerative colitis by autophagy-mediated NLRP3 inflammasome inactivation
Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 inflammasome has been considered to be a potential therapy, the underlying mechanism through which pathway the intestinal inflammat...
Autores principales: | Lv, Qi, Xing, Yao, Liu, Jian, Dong, Dong, Liu, Yue, Qiao, Hongzhi, Zhang, Yinan, Hu, Lihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463273/ https://www.ncbi.nlm.nih.gov/pubmed/34589402 http://dx.doi.org/10.1016/j.apsb.2021.03.011 |
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