Immunogenicity of stabilized HIV-1 Env trimers delivered by self-amplifying mRNA

Self-amplifying mRNA (saRNA) represents a promising platform for nucleic acid delivery of vaccine immunogens. Unlike plasmid DNA, saRNA does not require entry into the nucleus of target cells for expression, having the capacity to drive higher protein expression compared to mRNA as it replicates wit...

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Detalles Bibliográficos
Autores principales: Aldon, Yoann, McKay, Paul F., Moreno Herrero, Jorge, Vogel, Annette B., Lévai, Réka, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Haas, Heinrich, Fábián, Katalin, Le Grand, Roger, Sahin, Ugur, Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463288/
https://www.ncbi.nlm.nih.gov/pubmed/34589271
http://dx.doi.org/10.1016/j.omtn.2021.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463288/
https://www.ncbi.nlm.nih.gov/pubmed/34589271
http://dx.doi.org/10.1016/j.omtn.2021.06.008

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