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CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia

The utility of CRISPR-Cas9 to repair or reverse diseased states that arise from recent genetic mutations in the human genome is now widely appreciated. The use of CRISPR to “design” the outcomes of biology is challenged by both specialized ethicists and the general public. Less of a focus, however,...

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Detalles Bibliográficos
Autores principales: de Lima Balico, Lais, Gaucher, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463316/
https://www.ncbi.nlm.nih.gov/pubmed/34589279
http://dx.doi.org/10.1016/j.omtn.2021.08.002