Notch activation promotes endothelial quiescence by repressing MYC expression via miR-218

After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiescence, but the mechanisms of action remain elusive....

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Detalles Bibliográficos
Autores principales: Sun, Jia-Xing, Dou, Guo-Rui, Yang, Zi-Yan, Liang, Liang, Duan, Juan-Li, Ruan, Bai, Li, Man-Hong, Chang, Tian-Fang, Xu, Xin-Yuan, Chen, Juan-Juan, Wang, Yu-Sheng, Yan, Xian-Chun, Han, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463319/
https://www.ncbi.nlm.nih.gov/pubmed/34589277
http://dx.doi.org/10.1016/j.omtn.2021.07.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463319/
https://www.ncbi.nlm.nih.gov/pubmed/34589277
http://dx.doi.org/10.1016/j.omtn.2021.07.023

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