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Chimeric RNA-binding protein-based killing switch targeting hepatocellular carcinoma cells

Cancer cell-specific killing switches are synthetic circuits developed as an intelligent weapon to specifically eliminate malignant cells. RNA-delivered synthetic circuits provide safer means to control oncolytic functions, in which proteolysis-responding capsid-cNOT7 is developed to enable logic co...

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Detalles Bibliográficos
Autores principales: Yang, Jiong, Ding, Shigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463442/
https://www.ncbi.nlm.nih.gov/pubmed/34589286
http://dx.doi.org/10.1016/j.omtn.2021.08.012