Preparation, characterization, dissolution, and permeation of flibanserin − 2-HP-β-cyclodextrin inclusion complexes

Flibanserin (FLB), an antiserotonin drug, is used to treat women with hypoactive sexual appetite disorder. FLB shows low bioavailability (~33%) probably due to its low water solubility. The current study investigated the impact of hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium lauryl sulfate (SLS...

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Detalles Bibliográficos
Autores principales: Alghaith, Adel F., Mahrous, Gamal M., Zidan, Diaa Eldin, Alhakamy, Nabil A., Alamoudi, Abdulmohsin J., Radwan, Awwad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463492/
https://www.ncbi.nlm.nih.gov/pubmed/34588842
http://dx.doi.org/10.1016/j.jsps.2021.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463492/
https://www.ncbi.nlm.nih.gov/pubmed/34588842
http://dx.doi.org/10.1016/j.jsps.2021.07.019

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