Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease

Development of cholesteryl ester transfer protein (CETP) inhibitors for coronary heart disease (CHD) has yet to deliver licensed medicines. To distinguish compound from drug target failure, we compared evidence from clinical trials and drug target Mendelian randomization of CETP protein concentratio...

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Detalles Bibliográficos
Autores principales: Schmidt, Amand F., Hunt, Nicholas B., Gordillo-Marañón, Maria, Charoen, Pimphen, Drenos, Fotios, Kivimaki, Mika, Lawlor, Deborah A., Giambartolomei, Claudia, Papacosta, Olia, Chaturvedi, Nishi, Bis, Joshua C., O’Donnell, Christopher J., Wannamethee, Goya, Wong, Andrew, Price, Jackie F., Hughes, Alun D., Gaunt, Tom R., Franceschini, Nora, Mook-Kanamori, Dennis O., Zwierzyna, Magdalena, Sofat, Reecha, Hingorani, Aroon D., Finan, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463530/
https://www.ncbi.nlm.nih.gov/pubmed/34561430
http://dx.doi.org/10.1038/s41467-021-25703-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463530/
https://www.ncbi.nlm.nih.gov/pubmed/34561430
http://dx.doi.org/10.1038/s41467-021-25703-3

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