ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron

Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by ferrous iron and H(2)O(2) via Fenton reaction, in which the role of activating transcription factor 3 (ATF3) remains elusive. Brucine is a weak alkaline indole alkaloid extracted from the seeds of Stryc...

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Detalles Bibliográficos
Autores principales: Lu, Shan, Wang, Xuan-zhong, He, Chuan, Wang, Lei, Liang, Shi-peng, Wang, Chong-cheng, Li, Chen, Luo, Tian-fei, Feng, Chun-sheng, Wang, Zhen-chuan, Chi, Guang-fan, Ge, Peng-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463534/
https://www.ncbi.nlm.nih.gov/pubmed/34112960
http://dx.doi.org/10.1038/s41401-021-00700-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463534/
https://www.ncbi.nlm.nih.gov/pubmed/34112960
http://dx.doi.org/10.1038/s41401-021-00700-w

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