Cargando…
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron
Ferroptotic cell death is characterized by iron-dependent lipid peroxidation that is initiated by ferrous iron and H(2)O(2) via Fenton reaction, in which the role of activating transcription factor 3 (ATF3) remains elusive. Brucine is a weak alkaline indole alkaloid extracted from the seeds of Stryc...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Singapore
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463534/ https://www.ncbi.nlm.nih.gov/pubmed/34112960 http://dx.doi.org/10.1038/s41401-021-00700-w |