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In vivo analysis of onset and progression of retinal degeneration in the Nr2e3(rd7/rd7) mouse model of enhanced S-cone sensitivity syndrome

The photoreceptor-specific nuclear receptor Nr2e3 is not expressed in Nr2e3(rd7/rd7) mice, a mouse model of the recessively inherited retinal degeneration enhanced S-cone sensitivity syndrome (ESCS). We characterized in detail C57BL/6J Nr2e3(rd7/rd7) mice in vivo by fundus photography, optical coher...

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Detalles Bibliográficos
Autores principales: Venturini, Giulia, Kokona, Despina, Steiner, Beatrice L., Bulla, Emanuele G., Jovanovic, Joel, Zinkernagel, Martin S., Escher, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463594/
https://www.ncbi.nlm.nih.gov/pubmed/34561487
http://dx.doi.org/10.1038/s41598-021-98271-7