Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

Comparing transcript levels between healthy and diseased individuals allows the identification of differentially expressed genes, which may be causes, consequences or mere correlates of the disease under scrutiny. We propose a method to decompose the observational correlation between gene expression...

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Detalles Bibliográficos
Autores principales: Porcu, Eleonora, Sadler, Marie C., Lepik, Kaido, Auwerx, Chiara, Wood, Andrew R., Weihs, Antoine, Sleiman, Maroun S. Bou, Ribeiro, Diogo M., Bandinelli, Stefania, Tanaka, Toshiko, Nauck, Matthias, Völker, Uwe, Delaneau, Olivier, Metspalu, Andres, Teumer, Alexander, Frayling, Timothy, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463674/
https://www.ncbi.nlm.nih.gov/pubmed/34561431
http://dx.doi.org/10.1038/s41467-021-25805-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8463674/
https://www.ncbi.nlm.nih.gov/pubmed/34561431
http://dx.doi.org/10.1038/s41467-021-25805-y

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